2019, Cilt 35, Sayı 4, Sayfa(lar) 230-235
The determination of polymorphisms between 6-9 exons of the water buffalo STAT5A gene
Emsal İbiş1, Metin Erdoğan2
1Department Medical Documentation and Secretarial, Gediz Health Services Vocational School Kutahya University of Health Sciences, Kutahya, Turkey
sup>Department of Medical Biology and Genetics, Faculty of Veterinary Medicine, Afyon Kocatepe University, Afyonkarahisar, Turkey
Keywords: Anatolian Water Buffaloes, gene polymorphism, SNP, STAT5A
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Aim: The aim of this study was to determine the polymorphisms between 6th-9th exons of STAT5A gene which affects milk yield and milk composition in Anatolian buffaloes.

Materials and Methods: The material of the study was composed of the blood samples taken from 96 Anatolian buffaloes grown in Afyonkarahisar region.

Results: According to the results of the research, g+12221 C> T polymorphism was detected in the 8th exon of STAT5A gene.

Conclusion: The signal transducer and transcription activator 5A gene (signal transducers and activators of transcription 5A, STAT5A) is important in dairy animal breeding because it has many vital tasks within the cell as well in addition to affecting milk yield and composition. In this study, the polymorphism in the 8th exon was described as a silent mutation since protein synthesis did not cause a change in amino acid sequence. In order to make the breeding studies more efficient, it is important to increase the studies on STAT5A gene, which affects milk yield and milk composition in mammals.