Aim: The objective of this study was to evaluate the presence of quinolone antibiotic residues (ciprofloxacin, enrofloxacin, marbofloxacin, danofloxacin, difloxacin, flumequin, sarafloxacin and oxolinic acid) in raw milk and chicken liver samples in Konya.

Materials and Methods: A total of 100 samples, including 50 raw milk and 50 chicken liver samples, were examined for quinolone antibiotics. The samples were analyzed by an enzyme-linked immunosorbent assay (ELISA) screening method.

Results: Of the 50 chicken liver samples analyzed for residues of quinolone, 17 (34%) were positive and in one of them the value (147.88 μg/kg) was above the maximum residue limits (MRLs). The mean contamination level was 47.5 μg/kg. None of the milk samples were found to be positive for quinolone residues.

Conclusion: All of the analyzed samples except one showed the presence of quinolone residues below the MRLs established by European Union (EU) and Turkish Legislation. So that obtained results from analysis of milk and chicken liver samples were considered to be a positive sign in terms of food safety. Also these analyses are performed as routine according to the National Residue Monitoring Plan of the Republic of Turkey. Therefore, routine drug residues surveillance and monitoring programs in edible animal products like milk, meat and eggs should be continued to ensure food safety in the country.