The present experiment was carried out to investigate the changes occuring calcium, sodium, potassium, magnesium and copper levels ln the blood of the sheep experimantally poisoned with amygdalin. In the study twenty ewes. aged approximately two years old were used. The animal an which the experiment was made was fasted trom 5 p.m. a day ago to the complement of experiment the next day. Thus. cyanide contamination due to feed and water were prevented Amygdalin was given through the rumen probe in doses of 0.25. 0.5. 1.0, 1.5 mg/kg. Samples of the blood were collected at 1 ,2,4,8,24.48,72. hours alter amygdaline was given. Samples of the blood were analysed in terms of the levels calcium, sodium, potassium, magnesium and copper. In conclusion, the levels of sodium, potassium and calcium were observed to increase experimentally in the cyanide poisoning. On the other hand, the levels of magnesium and copper were determined to decrease experimentally in the cyanide poisoning.