Fasciola hepatica is an important disease of livestock and wild ruminants (especially destroyed tiver and bile ducts), and causing significant morbidity with grave economic losses. Due to the fact that liver have important roles metabolic roles, the amounts of liver zinc, copper and iron concentrations may have altered in lambs during Fasciola hepatica invasion. The study materials were consisted 20 liver and kidney specimens belong to iambs with Fasciola hepatica slaughtered (infected group) in Diyarbakır Et ve Balık Kurumu Slaughterhouse and 20 liver and kidney specimens came from healthy lambs . We measured copper, iron and zinc levels in livers and kidneys by using Atomic Absorbtion Spectrometry. The data of trace elements were expressed in rng/g/wet weight. The value for liver copper (Cu) (441.514 mg/g} was not found a significant decreasing (p> 0.05) when compared the control group (42.473 mg/g). The values for liver ferrum (Fe) and zinc (Zn) concentraions (respectively; 23.674 and 15.569 mg/g) was found a significant decreasing (respectively; p< 0,05 and p>0.001) when compared the control group (respectively: 31.785 and 22.730 mg/g ) . The values for kidney Cu, Fe and Zn was not found a significant decreasing (p> 0.05) when compared the control group The results of this study indicated thai Fasciola hepatica invasion might have had some effects on liver Fe and Zn concentrations, but not liver Cu concentration. Therefore, no significant differences were found in Cu, Fe and Zn concentrations when compared the control group.